FAQ: Biomarker Reference Ranges

Here’s a quick overview of how our Everlab reference ranges work and why these are different to pathology clinics:
 

They’re not one-size-fits-all. 

Some biomarkers have reference ranges that are adjusted for age and sex (e.g. testosterone, ferritin, visceral fat, strength metrics), while others use a universal range (e.g. apoB, Lp(a)). A small number of markers — like B12, B6, and DHEA — don’t have a clearly defined “optimal” upper range, and these are carefully reviewed by our medical team based on the latest research.

We use multiple sources. 

Our ranges are drawn from a wide range of guidelines including the Royal College of Pathologists Australia, the WHO, Australian and international clinical guidelines, published literature, and longevity medicine research. For some markers (like apoB, LDL, hs-CRP, ALT, and bone density), we deliberately set more preventative targets that are more aggressive than standard diagnostic ranges, because our focus is on long-term health optimisation, not just detecting disease.

Local lab methodology matters. 

Reference ranges can vary depending on the lab equipment and measurement methods used, so we validate our ranges against local laboratory data where relevant. This is especially important for hormone markers.

Some targets are personal. 

For certain biomarkers, what’s “optimal” depends on your individual genetics, risk factors, and health history. For example, someone with existing cardiovascular disease may need a much lower apoB target than the general population. Where personalised targets are relevant, we recommend discussing your specific results with your doctor.

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Check out our activity page tracking reference range changes.